YRP12117-01 [Polyclonal Antibody]
CHRNA6 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB FC IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human CHRNA6
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:  
Swiss Prot:  
Synonyms:   AChR-alpha6, Acra6, Cholinergic receptor nicotinic alpha 6, Cholinergic receptor nicotinic alpha polypeptide 6, CHRNA 6, nAChR alpha 6, NACHRA6, Neuronal acetylcholine receptor subunit alpha 6, Nicotinic acetylcholine receptor alpha6, ACHA6_HUMAN.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters. Two important members of this family are the nicotinic acetylcholine and glutamate receptors, both of which are composed of five homologous subunits forming a transmembrane aqueous pore. These transmembrane receptors change conformation in response to their cognate neurotransmitter. Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, allowing ions to move through the pore. AChR alpha 6, also designated cholinergic nicotinic receptor alpha polypeptide 6, is a neuronal acetylcholine receptor protein expressed in respiratory mucosa. AChR alpha 6 is also selectively expressed on dopaminergic terminals, where it complexes with AChR Beta 2 and AChR alpha 4.
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
FC 1:20-1:100
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information