MRM93759-21S
[Monoclonal Antibody]
SIRT1 Rabbit Monoclonal Antibody (Mouse Specific)
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Species: |
Rabbit |
Applications: |
WB IP |
Immunogen Range: |
A synthetic peptide corresponding to the carboxy terminus of mouse SirT1 |
Clonality: |
Monoclonal Antibody |
Isotype: |
IgG |
GENE ID: |
93759(Mouse) |
Swiss Prot: |
Q923E4 |
Synonyms: |
Sir2, Sir2a, SIR2L1, AA673258, Sir2alpha |
Purification: |
Affinity purification |
Storage: |
Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq |
Caculated MW: |
120 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:1000
|
Reacitivity: |
Mouse |
For research use only. Not intended for diagnostic or therapeutic use!