ARP1742P-21 [Polyclonal Antibody]
Phospho-DLG4-Tyr236/Tyr240 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic phosphopeptide corresponding to residues surrounding Tyr236 and Tyr240 of human PSD95
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   1742
Swiss Prot:   P78352
Synonyms:   PSD95, SAP90, SAP-90
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Postsynaptic Density protein 95 (PSD95) is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. These family members consist of an amino-terminal variable segment followed by three PDZ domains, a SH3 domain and an inactive guanylate kinase (GK) domain. PSD95 is a scaffolding protein involved in the assembly and function of the postsynaptic density complex (1-2). PSD95 participates in synaptic targeting of AMPA receptors through an indirect manner involving Stargazin and related transmembrane AMPA receptor regulatory proteins (TARPs) (3). It is implicated in experience dependent plasticity and plays an indispensable role in learning (4). Mutations in PSD95 are associated with autism (5).
Caculated MW:   95 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:1000
Reacitivity:   Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information