ARP1581-31 [Polyclonal Antibody]
CYP7A1 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC ELISA IP IF
Immunogen Range:   A synthetic peptide derived from human CYP7A1
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   1581
Swiss Prot:   P22680
Synonyms:   CP7A, CYP7, CYPVII
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis.
Caculated MW:   55 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:500
IHC 1:100-1:500
IF 1:100-1:500
Reacitivity:   Guinea pig, Human, Mouse, Pig, Rat, Rabbit
For research use only. Not intended for diagnostic or therapeutic use!
Additional information