ARP6789-21 [Polyclonal Antibody]
Phospho-STK4-Thr183/STK3-Thr180 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic phosphopeptide corresponding to residues surrounding Thr183 of human Mst1
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   6789
Swiss Prot:   Q13043
Synonyms:   DKFZp686A2068, KRS2, MST1, YSK3
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process. [provided by RefSeq
Caculated MW:   59 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:1000
Reacitivity:   Guinea pig, Human, Mouse
For research use only. Not intended for diagnostic or therapeutic use!
Additional information