ARM10461-21C
[Monoclonal Antibody]
MERTK Rabbit Monoclonal Antibody (Sepharose Bead Conjugate)
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DATASHEET
| Species: |
Rabbit |
| Applications: |
IP |
| Immunogen Range: |
A synthetic peptide corresponding to residues surrounding His925 of human Mer protein |
| Clonality: |
Monoclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
10461 |
| Swiss Prot: |
Q12866 |
| Synonyms: |
MER, MGC133349, RP38, c-mer |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). |
| Caculated MW: |
210 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
|
| Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!