ARM3098-22C [Monoclonal Antibody]
HK1 Rabbit Monoclonal Antibody (Alexa Fluor(R) 647 Conjugate)
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Species:   Rabbit
Applications:   IF FC
Immunogen Range:   /
Clonality:   Monoclonal Antibody
Isotype:   /
GENE ID:   3098
Swiss Prot:   P19367
Synonyms:   HK1, HK1-ta, HK1-tb, HK1-tc, HKI, HXK1
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Hexokinase catalyzes the conversion of glucose to glucose-6-phosphate, the first step in glycolysis. Four distinct mammalian hexokinase isoforms, designated as hexokinase I, II, III, and IV (glucokinase), have been identified. Hexokinases I, II, and III are associated with the outer mitochondrial membrane and are critical for maintaining an elevated rate of aerobic glycolysis in cancer cells (Warburg Effect) (1) in order to compensate for the increased energy demands associated with rapid cell growth and proliferation (2,3).
Caculated MW:   102 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   /
For research use only. Not intended for diagnostic or therapeutic use!
Additional information