Species: | Rabbit |
Applications: | WB IHC ELISA IF |
Immunogen Range: | A synthetic peptide derived from human CD339 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 182 |
Swiss Prot: | P78504 |
Synonyms: | AGS, AHD, AWS, HJ1, CD339, JAGL1 |
Purification: | Affinity purification |
Storage: | Store at -20°C or in lyophilized state. Avoid freeze/thaw cycles. |
Background: | The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. |
Caculated MW: | 134 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:500 IHC 1:100-1:500 IF 1:100-1:500 |
Reacitivity: | Human, Mouse, Rat |