HRM4791-21S [Monoclonal Antibody]
NFKB2 p100/p52 Rabbit Monoclonal Antibody (Human Specific)
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Species:   Rabbit
Applications:   WB IHC FC
Immunogen Range:   A synthetic peptide corresponding to residues at the amino-terminus of human NF-kappaB2 p100/p52
Clonality:   Monoclonal Antibody
Isotype:   /
GENE ID:   4791
Swiss Prot:   Q00653
Synonyms:   p52, p105, H2TF1, LYT10, LYT-10, NF-kB2
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene encodes one of the subunits of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB transcription factor complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The NFkB complex can consist of different subunits that form both homo- or heterodimers which bind specific kappa-B elements in target genes. This gene encodes the p100 subunit that is processed into the active p52 subunit. This protein can function as both a transcriptional activator and repressor, depending on its dimer partner. Alternate splicing results in both coding and non-coding variants.
Caculated MW:   52 kDa active form. 120 kDa precursor.
Observed MW:   Refer to Figures
Applications:   WB 1:1000
IHC 1:300
FC 1:50
Reacitivity:   Human, Monkey
For research use only. Not intended for diagnostic or therapeutic use!
Additional information