ORP20304-21S [Polyclonal Antibody]
CCL5 Rabbit Polyclonal Antibody (Rodent Specific)
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Species:   Rabbit
Applications:   WB IP
Immunogen Range:   A synthetic peptide corresponding to residues at the carboxyl terminus of rodent RANTES
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   20304(Mouse)/81780(Rat)
Swiss Prot:   P30882/P50231
Synonyms:   SISd, Scya5, RANTES, TCP228, MuRantes
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms.
Caculated MW:   10 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:1000
Reacitivity:   Mouse
For research use only. Not intended for diagnostic or therapeutic use!
Additional information