HRP578-21S
[Polyclonal Antibody]
BAX Rabbit Polyclonal Antibody (Human Specific)
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB IHC IP |
| Immunogen Range: | A synthetic peptide corresponding to residues surrounding lysine 58 of human Bax |
| Clonality: | Polyclonal Antibody |
| Isotype: | / |
| GENE ID: | 581 |
| Swiss Prot: | Q07812 |
| Synonyms: | BCL2L4 |
| Purification: | Affinity purification |
| Storage: | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | Bax is a key component for cellular induced apoptosis through mitochondrial stress (1). Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane (2). Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis (3,4). |
| Caculated MW: | 20 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:1000 IHC 1:100 |
| Reacitivity: | Human, Monkey |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information