ARP6622-21S [Polyclonal Antibody]
SNCA Rabbit Polyclonal Antibody (IF Preferred)
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Species:   Rabbit
Applications:   WB IF
Immunogen Range:   A synthetic peptide corresponding to the carboxy terminus of mouse synuclein
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   6622
Swiss Prot:   P37840
Synonyms:   TLR7-like, MGC110988, NACP, PARK1, PARK4, PD1
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   α-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq
Caculated MW:   18 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:1000
IF 1:50
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information