ARP6622-21S
[Polyclonal Antibody]
SNCA Rabbit Polyclonal Antibody (IF Preferred)
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Species: |
Rabbit |
Applications: |
WB IF |
Immunogen Range: |
A synthetic peptide corresponding to the carboxy terminus of mouse synuclein |
Clonality: |
Polyclonal Antibody |
Isotype: |
/ |
GENE ID: |
6622 |
Swiss Prot: |
P37840 |
Synonyms: |
TLR7-like, MGC110988, NACP, PARK1, PARK4, PD1 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
α-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq |
Caculated MW: |
18 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:1000 IF 1:50
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!