ARP5499P-21
[Polyclonal Antibody]
Phospho-PP1CA-Thr320 Rabbit Polyclonal Antibody
www.yhsbio.com
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support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB IHC |
| Immunogen Range: | A synthetic phosphopeptide corresponding to residues surrounding Thr320 of human PP1α |
| Clonality: | Polyclonal Antibody |
| Isotype: | / |
| GENE ID: | 5499 |
| Swiss Prot: | P62136 |
| Synonyms: | PPP1CA, MGC15877, MGC1674, PP-1A, PP1alpha, PPP1A |
| Purification: | Affinity purification |
| Storage: | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | Type 1 protein phosphatase (PP1), a serine/threonine phosphatase, is highly conserved in eukaryotic cells. Four isoforms of PP1 have been characterized: PP1α, PP1δ, PP1γ1 and PP1γ2 (1). Involvement in cell cycle regulation is one of the biological functions of PP1 (1). It has been illustrated that PP1 dephosphorylates Rb and cdc25 during mitosis (2,3). A cell cycle-dependent phosphorylation at Thr320 of PP1α by cdc2 kinase inhibits PP1α activity (4). |
| Caculated MW: | 38 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:1000 IHC 1:50 |
| Reacitivity: | Human, Monkey, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information