ARPF021-21
[Polyclonal Antibody]
EIF4A Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB |
| Immunogen Range: | A synthetic peptide corresponding to residues surrounding Phe52 of human eIF4A |
| Clonality: | Polyclonal Antibody |
| Isotype: | / |
| GENE ID: | 1973/1974/9775 |
| Swiss Prot: | P60842/Q14240/P38919 |
| Synonyms: | / |
| Purification: | Affinity purification |
| Storage: | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | A variety of factors contribute to the important biological event of initiation of translation. The eIF4F complex of translation initiation factors binds to the 5' m7 GTP cap to open up the mRNA secondary structure and allow small ribosome subunit binding (1). eIF4A, an eIF4 complex component that acts as an ATP-dependent RNA helicase, unwinds the secondary structure of the 5' mRNA untranslated region to mediate ribosome binding (2,3). In addition, eIF4A has recently been shown to repress Dpp/BMP signalling in a translation-independent manner in Drosophila (4,5). |
| Caculated MW: | 48 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:1000 |
| Reacitivity: | Human, Monkey, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information