ORP21898P-21S [Polyclonal Antibody]
TLR4 Rabbit Polyclonal Antibody (Rodent Specific)
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
Species:   Rabbit
Applications:   WB
Immunogen Range:   /
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   21898(Mouse)/29260(Rat)
Swiss Prot:   Q9QUK6/Q9QX05
Synonyms:   Lps, Ly87, Ran/M1, Rasl2-8
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Also, several transcript variants of this gene have been found, but the protein coding potential of most of them is uncertain.
Caculated MW:   110 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   /
For research use only. Not intended for diagnostic or therapeutic use!
Additional information