MRP12122-21S
[Polyclonal Antibody]
BID Rabbit Polyclonal Antibody (Mouse Specific)
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DATASHEET
| Species: |
Rabbit |
| Applications: |
WB |
| Immunogen Range: |
A synthetic peptide corresponding to residues surrounding the cleavage site of mouse BID |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
/ |
| GENE ID: |
12122(Mouse) |
| Swiss Prot: |
P70444 |
| Synonyms: |
2700049M22Rik, AI875481, AU022477 |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq |
| Caculated MW: |
22 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:1000
|
| Reacitivity: |
Mouse |
For research use only. Not intended for diagnostic or therapeutic use!