HRP637-21S
[Polyclonal Antibody]
BID Rabbit Polyclonal Antibody (Human Specific)
www.yhsbio.com
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Species: |
Rabbit |
Applications: |
WB IP |
Immunogen Range: |
A synthetic peptide corresponding to residues surrounding the cleavage site of human BID |
Clonality: |
Polyclonal Antibody |
Isotype: |
/ |
GENE ID: |
637 |
Swiss Prot: |
P55957 |
Synonyms: |
FP497, MGC15319, MGC42355 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq |
Caculated MW: |
15, 22 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:1000
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!