ARM51135P-21
[Monoclonal Antibody]
Phospho-IRAK4-Thr345/Ser346 Rabbit Monoclonal Antibody
www.yhsbio.com
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Species: |
Rabbit |
Applications: |
WB IP FC |
Immunogen Range: |
A synthetic phosphopeptide corresponding to residues surrounding Thr345/Ser346 of human IRAK4 protein |
Clonality: |
Monoclonal Antibody |
Isotype: |
IgG |
GENE ID: |
51135 |
Swiss Prot: |
Q9NWZ3 |
Synonyms: |
IPD1, REN64, IRAK-4, NY-REN-64 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. |
Caculated MW: |
55 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:1000 FC 1:400
|
Reacitivity: |
Human, (Mouse, Rat, Bovine, Dog) |
For research use only. Not intended for diagnostic or therapeutic use!