Species: | Rabbit |
Applications: | WB IHC ELISA IF |
Immunogen Range: | A synthetic peptide corresponding to amino acids 110-125 of human JAG1 |
Clonality: | Polyclonal Antibody |
Isotype: | / |
GENE ID: | 182 |
Swiss Prot: | P78504 |
Synonyms: | AGS, AHD, AWS, CD339, HJ1, JAGL1, MGC104644 |
Purification: | Affinity purification |
Storage: | Store at 4°C. For long term storage store at -20°C in 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide).Avoid freeze/thaw cycles. |
Background: | The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq |
Caculated MW: | 180 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:100-1:500 IF 1:200-1:1000 |
Reacitivity: | Dog, Human, Xenopus |