
| Species: | Rabbit |
| Applications: | WB IHC ELISA IF |
| Immunogen Range: | A synthetic peptide corresponding to amino acids 110-125 of human JAG1 |
| Clonality: | Polyclonal Antibody |
| Isotype: | / |
| GENE ID: | 182 |
| Swiss Prot: | P78504 |
| Synonyms: | AGS, AHD, AWS, CD339, HJ1, JAGL1, MGC104644 |
| Purification: | Affinity purification |
| Storage: | Store at 4°C. For long term storage store at -20°C in 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide).Avoid freeze/thaw cycles. |
| Background: | The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq |
| Caculated MW: | 180 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:2000 IHC 1:100-1:500 IF 1:200-1:1000 |
| Reacitivity: | Dog, Human, Xenopus |