ARP9262-11
[Polyclonal Antibody]
STK17B Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB |
| Immunogen Range: | A synthetic peptide corresponding to amino acids 351-365 of human STK17B |
| Clonality: | Polyclonal Antibody |
| Isotype: | / |
| GENE ID: | 9262 |
| Swiss Prot: | O94768 |
| Synonyms: | DRAK2 |
| Purification: | Affinity purification |
| Storage: | Store at -20°C in PBS (0.02% sodium azide).Avoid freeze/thaw cycles. |
| Background: | DRAK2 (DAP kinase related apoptosis inducing protein kinase 2) is a member of the novel DAP (death associated protein) pro-apoptotic kinase family (1). Overexpression of DRAK2 in NIH/3T3 cells induces morphological changes associated with apoptosis, which are likely to occur in a p53-dependent manner (1,2). DRAK2 is preferentially expressed in lymphoid tissues and regulates the TCR activation threshold during thymocyte selection (3). Indeed, T cells from DRAK2(-/-) mice exhibit enhanced sensitivity to T cell receptor-mediated stimulation and have a reduced requirement for co-stimulation (4). |
| Caculated MW: | 43 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 0.5-1 ug/mL |
| Reacitivity: | Human |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information