ARPF007-11
[Polyclonal Antibody]
DNM1/2 Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
WB |
Immunogen Range: |
A synthetic peptide (conjugated with KLH) corresponding to human Dynamin |
Clonality: |
Polyclonal Antibody |
Isotype: |
/ |
GENE ID: |
1759/1785 |
Swiss Prot: |
Q05193/P50570 |
Synonyms: |
/ |
Purification: |
Affinity purification |
Storage: |
Store at -20°C in 10 mM HEPES, 150 mM NaCl, pH 7.5 (50% glycerol, 10% BSA.Avoid freeze/thaw cycles. |
Background: |
Dynamin is a family of large GTPases that has been implicated in the formation of vesicles of both the endocytotic and secretory processes (1). Dynamin plays an important role in the internalization of cell surface receptors, a process that attenuates the response to extracellular signals. It has been illustrated that dynamin interacts with signaling proteins such as Src, PLCγ, PKC and G-proteins. PKC and Src phosphorylate dynamin, and its phosphorylation may regulate the endocytosis of cell surface receptors (2,3). |
Caculated MW: |
100 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:1000
|
Reacitivity: |
Bovine, Chiken, Human, Mouse, Primates, Rat |
For research use only. Not intended for diagnostic or therapeutic use!