ARPF007-11 [Polyclonal Antibody]
DNM1/2 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic peptide (conjugated with KLH) corresponding to human Dynamin
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   1759/1785
Swiss Prot:   Q05193/P50570
Synonyms:   /
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM HEPES, 150 mM NaCl, pH 7.5 (50% glycerol, 10% BSA.Avoid freeze/thaw cycles.
Background:   Dynamin is a family of large GTPases that has been implicated in the formation of vesicles of both the endocytotic and secretory processes (1). Dynamin plays an important role in the internalization of cell surface receptors, a process that attenuates the response to extracellular signals. It has been illustrated that dynamin interacts with signaling proteins such as Src, PLCγ, PKC and G-proteins. PKC and Src phosphorylate dynamin, and its phosphorylation may regulate the endocytosis of cell surface receptors (2,3).
Caculated MW:   100 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:1000
Reacitivity:   Bovine, Chiken, Human, Mouse, Primates, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information