AMM3932-12
[Monoclonal Antibody]
LCK Mouse Monoclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
Species: |
Rabbit |
Applications: |
WB IHC IP |
Immunogen Range: |
A synthetic peptide corresponding to C-terminus of human LCK |
Clonality: |
Monoclonal Antibody |
Isotype: |
/ |
GENE ID: |
3932 |
Swiss Prot: |
P06239 |
Synonyms: |
LSK, YT16, p56lck, pp58lck |
Purification: |
Affinity purification |
Storage: |
Store at -20°C. For long term storage store at -80°C in PBS, pH 7.2 (30% glycerol, 0.5 mg/mL BSA, 0.01% thimerosal).Avoid freeze/thaw cycles. |
Background: |
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq |
Caculated MW: |
56 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 0.5-4 ug/mL IHC 20-25 ug/mL
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!