ARP64581-11 [Polyclonal Antibody]
CLEC7A Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic peptide corresponding to residues surrounding amino acids 161 of human CLEC7A
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   64581
Swiss Prot:   Q9BXN2
Synonyms:   BGR, CLECSF12, DECTIN1
Purification:   Affinity purification
Storage:   Store at -20°C. For long term storage store at -80°C in PBS, pH 7.2 (30% glycerol, 0.5 mg/mL BSA, 0.01% thimerosal).Avoid freeze/thaw cycles.
Background:   This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq
Caculated MW:   28 kDa
Observed MW:   Refer to Figures
Applications:   WB 0.5-4 ug/mL
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information