ARP604-11 [Polyclonal Antibody]
BCL6 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IP
Immunogen Range:   A synthetic peptide corresponding to C-terminus of human BCL6
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   604
Swiss Prot:   P41182
Synonyms:   BCL5, BCL6A, LAZ3, ZBTB27, ZNF51
Purification:   Affinity purification
Storage:   Store at -20°C. For long term storage store at -80°C in PBS, pH 7.2 (30% glycerol, 0.5 mg/mL BSA, 0.01% thimerosal).Avoid freeze/thaw cycles.
Background:   The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq
Caculated MW:   87-98 kDa
Observed MW:   Refer to Figures
Applications:   WB 0.5-4 ug/mL
IHC 20-40 ug/mL
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information