ARP84962-11
[Polyclonal Antibody]
JUB Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | IP ICC |
| Immunogen Range: | A recombinant GST fusion protein corresponding to human JUB |
| Clonality: | Polyclonal Antibody |
| Isotype: | / |
| GENE ID: | 84962 |
| Swiss Prot: | Q96IF1 |
| Synonyms: | Ajuba, MGC15563 |
| Purification: | Affinity purification |
| Storage: | Store at -20°C in PBS (0.1% proclin, 2.0% Block Ace).Avoid freeze/thaw cycles. |
| Background: | Ajuba belongs to the Zyxin/Ajuba family, members of which include LIMD1, LPP, Trip6 and Zyxin. Three LIM domains at the carboxy-terminus characterize this family of proteins. Zyxin/Ajuba family members associate with the actin cytoskeleton, are components of both cell-cell junction adhesive complex and integrin-mediated adhesive complex, and shuttle in and out of the nucleus (1). Ajuba is involved in Rac activation during cell migration and activates Aurora A in order to commit to mitosis (2-3). Ajuba and its family members also have an amino-terminal proline-rich pre-LIM region, and Ajuba augments ERK activation in a Ras-dependent manner (4). |
| Caculated MW: | 55 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
ICC 2-5 ug/mL |
| Reacitivity: | Human |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information