
| Species: | Rabbit |
| Applications: | WB FC IHC IF |
| Immunogen Range: | KLH conjugated synthetic peptide derived from human GABRB2/GABA A Receptor beta 2 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | |
| Swiss Prot: | |
| Synonyms: | GABA, GABAA receptor subunit beta-2, GABRB2, Gamma aminobutyric acid GABA A receptor, beta 2, Gamma aminobutyric acid A receptor beta 2, Gamma-aminobutyric acid receptor subunit beta-2, Gamma-aminobutyric-acid receptor subunit beta-2, GBRB2_HUMAN, |
| Purification: | Purified by Protein A. |
| Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Background: | GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. |
| Caculated MW: | / |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 FC 1:20-1:100 |
| Reacitivity: | Human, Mouse, Rat |