Species: | Rabbit |
Applications: | WB IHC ELISA FC |
Immunogen Range: | A synthetic peptide (conjugated with KLH) corresponding to internal region of human ACE2 |
Clonality: | Polyclonal Antibody |
Isotype: | / |
GENE ID: | 59272 |
Swiss Prot: | Q9BYF1 |
Synonyms: | ACEH, DKFZp434A014 |
Purification: | Protein G purification |
Storage: | Store at 4°C. For long term storage store at -20°C in PBS (0.09% sodium azide).Avoid freeze/thaw cycles. |
Background: | The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq |
Caculated MW: | 120-135 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:50-1:200 IHC 1:50-1:100 FC 1:10-1:50 |
Reacitivity: | Human |