ARP235683-11 [Polyclonal Antibody]
PRKD3 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC ELISA IF
Immunogen Range:   A synthetic peptide (conjugated with KLH) corresponding to internal region of human PRKD3
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   23683
Swiss Prot:   P57729
Synonyms:   EPK2, PKC-NU, PKD3, PRKCN, nPKC-NU
Purification:   Protein G purification
Storage:   Store at 4°C. For long term storage store at -20°C in PBS (0.09% sodium azide).Avoid freeze/thaw cycles.
Background:   Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members. [provided by RefSeq
Caculated MW:   110 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:500
IHC 1:50-1:100
IF 1:500
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information