ARP10988-12 [Polyclonal Antibody]
METAP2 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   IHC ELISA
Immunogen Range:   A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human METAP2
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   10988
Swiss Prot:   P50579
Synonyms:   MAP2, MNPEP, p67, p67eIF2
Purification:   Protein G purification
Storage:   Store at 4°C. For long term storage store at -20°C in PBS (0.09% sodium azide).Avoid freeze/thaw cycles.
Background:   This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq
Caculated MW:   63 kDa
Observed MW:   Refer to Figures
Applications:   IHC 1:10-1:50
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information