ARP10988-11
[Polyclonal Antibody]
METAP2 Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
WB ELISA |
| Immunogen Range: |
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human METAP2 |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
/ |
| GENE ID: |
10988 |
| Swiss Prot: |
P50579 |
| Synonyms: |
MAP2, MNPEP, p67, p67eIF2 |
| Purification: |
Protein G purification |
| Storage: |
Store at 4°C. For long term storage store at -20°C in PBS (0.09% sodium azide).Avoid freeze/thaw cycles. |
| Background: |
This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq |
| Caculated MW: |
63 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:100-1:500
|
| Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!