ARP23092-11 [Polyclonal Antibody]
ARHGAP26 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC ELISA
Immunogen Range:   A synthetic peptide (conjugated with KLH) corresponding to internal region of human ARHGAP26
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   23092
Swiss Prot:   Q9UNA1
Synonyms:   FLJ42530, GRAF, KIAA0621, OPHN1L, OPHN1L1
Purification:   Protein G purification
Storage:   Store at 4°C. For long term storage store at -20°C in PBS (0.09% sodium azide).Avoid freeze/thaw cycles.
Background:   GTPase Regulator Associated with Focal Adhesion Kinase-1 (GRAF1), is a GTPase-activating protein for the small G proteins RhoA and Cdc42 (1). It is composed of an N-terminal BAR domain, a PH domain, a RhoGAP domain, a proline-rich domain, and a C-terminal SH3 domain. GRAF1 contributes to the clathrin-independent carriers/GPI-enriched early endosomal compartments (CLIC/GEEC) pathway, and was the first specific protein component of this endocytic pathway to be discovered (2). GRAF1 was identified as an important protein necessary for adeno-associated virus 2 infection (3). In addition, research studies have linked GRAF1 to mental retardation (4), skeletal muscle differentiation (5), and myeloid leukemia (6,7).
Caculated MW:   92 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:500
IHC 1:50-1:100
Reacitivity:   Human, Mouse
For research use only. Not intended for diagnostic or therapeutic use!
Additional information