ARP6046-11
[Polyclonal Antibody]
BRD2 Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
WB IHC ELISA |
Immunogen Range: |
A synthetic peptide (conjugated with KLH) corresponding to internal region of human BRD2 |
Clonality: |
Polyclonal Antibody |
Isotype: |
/ |
GENE ID: |
6046 |
Swiss Prot: |
P25440 |
Synonyms: |
D6S113E, DKFZp686N0336, FLJ31942, FSH, FSRG1, KIAA9001, NAT, RING3, RNF3 |
Purification: |
Protein G purification |
Storage: |
Store at 4°C. For long term storage store at -20°C in PBS (0.09% sodium azide).Avoid freeze/thaw cycles. |
Background: |
This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene, but the full-length nature of some of these variants has not been determined. [provided by RefSeq |
Caculated MW: |
110 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:100-1:500 IHC 1:50-1:100
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!