ARP8394-11
[Polyclonal Antibody]
PIP5K1A Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB ELISA |
| Immunogen Range: | A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PIP5K1A |
| Clonality: | Polyclonal Antibody |
| Isotype: | / |
| GENE ID: | 8394 |
| Swiss Prot: | Q99755 |
| Synonyms: | / |
| Purification: | Protein G purification |
| Storage: | Store at 4°C. For long term storage store at -20°C in PBS (0.09% sodium azide).Avoid freeze/thaw cycles. |
| Background: | Phosphatidylinositol-5-phosphate 4-kinases (PIP4K) synthesize phosphatidylinositol-4,5-bisphosphate (PtdIns(4,5)P2), a key precursor in phosphoinositide signaling that directly modulates the activity of signaling proteins and cellular processes. There are two subfamilies of PIP kinases, type I and II, that generate PtdIns(4,5)P2 from distinct substrate pools. PIP4 type I kinases use PtdIns5P as a substrate, whereas PIP5 type II kinases use PtdIns4P (1,2). In mammalian cells, three isoforms of each PIP4K and PIP5K subfamily, encoded by distinct genes, have been characterized (3-7). All PIP kinases are stimulated by phosphatidic acid, extensively regulated by ARF and Rho GTPases, and inhibited by protein kinase A and PI-stimulated autophosphorylation (8). |
| Caculated MW: | 62 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:100-1:500 |
| Reacitivity: | Human |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information