ARP65266-13
[Polyclonal Antibody]
WNK4 Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
IHC |
| Immunogen Range: |
A recombinant protein corresponding to amino acids of human WNK4 |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
65266 |
| Swiss Prot: |
Q96J92 |
| Synonyms: |
PHA2B, PRKWNK4 |
| Purification: |
Antigen affinity purification |
| Storage: |
Store at 4°C. For long term storage store at -20°C in PBS, pH 7.2, (40% glycerol, 0.02% sodium azide).Avoid freeze/thaw cycles. |
| Background: |
This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB |
| Caculated MW: |
135-140 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
IHC 1:20-1:50
|
| Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!