ARPF005-11 [Polyclonal Antibody]
PRKAA1/2 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   IHC
Immunogen Range:   A synthetic peptide corresponding to residues surrounding S485/S491 of human PRKAA1/PRKAA2
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   5562/5563
Swiss Prot:   Q13131/P54646
Synonyms:   AMPK, AMPKa1, MGC33776, MGC57364
Purification:   Affinity chromatography
Storage:   Store at -20°C in PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).Avoid freeze/thaw cycles.
Background:   The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq
Caculated MW:   62 kDa
Observed MW:   Refer to Figures
Applications:   IHC 1:50-1:100
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information