ARP6295-01 [Polyclonal Antibody]
SAG Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   A synthetic peptide corresponding to SAG
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   6295
Swiss Prot:   P10523
Synonyms:   DKFZp686D1084, DKFZp686I1383, S-AG
Purification:   Ammonium sulfate precipitation
Storage:   Store at 4°C. For long term storage store at -20°C in 1x PBS, pH 7.2 (0.05% sodium azide).Avoid freeze/thaw cycles.
Background:   Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness. [provided by RefSeq
Caculated MW:   47 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:1000
IHC 1:50-1:200
IF 1:50-1:200
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information