ARP706-11
[Polyclonal Antibody]
TSPO Rabbit Polyclonal Antibody
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DATASHEET
Species: |
Rabbit |
Applications: |
IHC |
Immunogen Range: |
A recombinant protein corresponding to amino acids of human ZNF706 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
706 |
Swiss Prot: |
P30536 |
Synonyms: |
HSPC038, PNAS-106, PNAS-113 |
Purification: |
Antigen affinity purification |
Storage: |
Store at 4°C. For long term storage store at -20°C in PBS, pH 7.5 (40% glycerol, 0.02% sodium azide).Avoid freeze/thaw cycles. |
Background: |
Translocator protein (TSPO) is an 18 kDa mitochondrial drug- and cholesterol-transporting protein involved in steroid hormone synthesis and mitochondrial homeostasis in a variety of cell types (1,2). Originally thought to play a role exclusively in steroid synthesis in steroidogenic cells, subsequent research studies have implicated TSPO in a variety of pathologies in a broad range of tissues including progression of breast cancer, neuroinflammation, and neurological disorders (1,3-5). TSPO was first identified by its ability to bind benzodiazepines in peripheral tissues and glial cells, hence its alternate name Peripheral Benzodiazepine Receptor (PBR). |
Caculated MW: |
18 kDa |
Observed MW: |
Refer to Figures |
Applications: |
IHC 1:200-1:500
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!