YRP12052-01
[Polyclonal Antibody]
5HT1E Receptor/SR-1E Rabbit Polyclonal Antibody
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DATASHEET
Species: |
Rabbit |
Applications: |
IHC IF |
Immunogen Range: |
KLH conjugated synthetic peptide derived from human 5HT1E Receptor/SR-1E |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
|
Swiss Prot: |
|
Synonyms: |
5 hydroxytryptamine serotonin receptor 1E, 5 hydroxytryptamine serotonin receptor 1E G protein coupled, 5 hydroxytryptamine 1E receptor, 5-HT-1E, 5-hydroxytryptamine receptor 1E, HTR1E, S31, Serotonin receptor 1E, 5HT1E_HUMAN. |
Purification: |
Purified by Protein A. |
Storage: |
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: |
The members of the G-protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. b-adrenergic bound to adrenaline activates adenylyl cyclase, while a2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the a2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-1–7 (5HT1–7). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F. |
Caculated MW: |
/ |
Observed MW: |
Refer to Figures |
Applications: |
IHC 1:100-1:500 IF 1:50-1:200
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!