ARP51247-11
[Polyclonal Antibody]
PAIP2 Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | IHC |
| Immunogen Range: | A recombinant protein corresponding to amino acids of human PAIP2 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 51247 |
| Swiss Prot: | Q9BPZ3 |
| Synonyms: | MGC72018, PAIP2A |
| Purification: | Antigen affinity purification |
| Storage: | Store at 4°C. For long term storage store at -20°C in PBS, pH 7.5 (40% glycerol, 0.02% sodium azide).Avoid freeze/thaw cycles. |
| Background: | The eukaryotic mRNA 3' poly(A) tail interacts with the 5' cap structure to regulate translation of mRNA transcripts (1). The eIF4G translation initiation factor associates with poly(A) binding protein (PABP) to circularize mRNA (1,2). Paip1 is a PABP interacting protein that binds eIF4A to stimulate translation (3). A second PABP binding protein, Paip2, inhibits translation by interfering with PABP function. Specifically, Paip2 reduces the affinity of PABP for poly(A) RNA and competes with Paip1 for PABP binding (1,2). |
| Caculated MW: | 25 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
IHC 1:200-1:500 |
| Reacitivity: | Human |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information