ARP51230-11
[Polyclonal Antibody]
PHF20 Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Mouse |
| Applications: | IHC |
| Immunogen Range: | A recombinant protein corresponding to full length human RB1 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG1 |
| GENE ID: | 51230 |
| Swiss Prot: | Q9BVI0 |
| Synonyms: | OSRC, RB, p105-Rb, pRb, pp110 |
| Purification: | Affinity purification |
| Storage: | Store at 4°C in PBS (0.2% gelatin, 0.1% sodium azide). Do not freeze. |
| Background: | The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq |
| Caculated MW: | 150 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
IHC 1:200-1:500 |
| Reacitivity: | Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information