ARP10451-11 [Polyclonal Antibody]
VAV3 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   IHC
Immunogen Range:   A recombinant protein corresponding to amino acids of human VAV3
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   10451
Swiss Prot:   Q9UKW4
Synonyms:   FLJ40431
Purification:   Antigen affinity purification
Storage:   Store at 4°C. For long term storage store at -20°C in PBS, pH 7.5 (40% glycerol, 0.02% sodium azide).Avoid freeze/thaw cycles.
Background:   This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
Caculated MW:   98 kDa
Observed MW:   Refer to Figures
Applications:   IHC 1:10-1:20
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information