ARP9698-01 [Polyclonal Antibody]
PUM1 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC ELISA
Immunogen Range:   A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PUM1
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   9698
Swiss Prot:   Q14671
Synonyms:   HSPUM, KIAA0099, PUMH, PUMH1, PUML1
Purification:   Protein A purification
Storage:   Store at 4°C. For long term storage store at -20°C in PBS (0.09% sodium azide).Avoid freeze/thaw cycles.
Background:   This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq
Caculated MW:   140 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:50-1:100
IHC 1:10-1:50
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information