ARP64332-11
[Polyclonal Antibody]
NFKBIZ Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | IHC |
| Immunogen Range: | A recombinant protein corresponding to amino acids of human KIAA0907 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 64332 |
| Swiss Prot: | Q9BYH8 |
| Synonyms: | RP11-336K24.1 |
| Purification: | Antigen affinity purification |
| Storage: | Store at 4°C. For long term storage store at -20°C in PBS, pH 7.5 (40% glycerol, 0.02% sodium azide).Avoid freeze/thaw cycles. |
| Background: | The NF-κB/Rel transcription factors are present in the cytosol in an inactive state complexed with the inhibitory IκB proteins (1-3). Activation occurs via phosphorylation of IκBα at Ser32 and Ser36 followed by proteasome-mediated degradation that results in the release and nuclear translocation of active NF-κB (3-7). IκBα phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory cytokines, growth factors, and chemokines. Kinases that phosphorylate IκB at these activating sites have been identified (8). |
| Caculated MW: | 85 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
IHC 1:20-1:50 |
| Reacitivity: | Human |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information