ARP7049-11
[Polyclonal Antibody]
TGFBR3 Rabbit Polyclonal Antibody
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DATASHEET
Species: |
Rabbit |
Applications: |
IHC |
Immunogen Range: |
A recombinant protein corresponding to amino acids of human TGFBR3 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
7049 |
Swiss Prot: |
Q03167 |
Synonyms: |
BGCAN, betaglycan |
Purification: |
Antigen affinity purification |
Storage: |
Store at 4°C. For long term storage store at -20°C in PBS, pH 7.5 (40% glycerol, 0.02% sodium azide).Avoid freeze/thaw cycles. |
Background: |
Transforming growth factor (TGF)-beta is a multifunctional cytokine that modulates several tissue development and repair processes, including cell differentiation, cell cycle progression, cellular migration, adhesion, and extracellular matrix production. Three TGF-beta forms are encoded by separate genes: TGFB1 (MIM 190180), TGFB2 (MIM 190220), and TGFB3 (MIM 190230). The diverse effects of TGF-beta are mediated by the TGF-beta receptors and cell surface-binding proteins. Three TGF-beta receptors exist: type I (TGFBR1; MIM 190181), type II (TFGBR2; MIM 190182), and type III (TGFBR3). TGFBR3 is a glycoprotein that binds TGFB and exists in both a membrane-bound and a soluble form (Johnson et al., 1995 [PubMed 8530052]).[supplied by OMIM |
Caculated MW: |
110 kDa |
Observed MW: |
Refer to Figures |
Applications: |
IHC 1:50-1:200
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!