ARP55004-11 [Polyclonal Antibody]
C11orf59 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   A recombinant protein corresponding to amino acids of human C11orf59
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   55004
Swiss Prot:   Q6IAA8
Synonyms:   FLJ20625
Purification:   Antigen affinity purification
Storage:   Store at 4°C. For long term storage store at -20°C in PBS, pH 7.5 (40% glycerol, 0.02% sodium azide).Avoid freeze/thaw cycles.
Background:   mTORC1 kinase complex is a critical component in the regulation of cell growth (1,2). Its activity is modulated by energy levels, growth factors, and amino acids (3,4). The four related GTPases, RagA, RagB, RagC, and RagD, have been shown to interact with raptor in mTORC1 (1,2). These interactions are both necessary and sufficient for mTORC1 activation in response to amino acid signals (1,2). A protein complex consisting of LAMTOR1/C11orf59, LAMTOR2/ROBLD3, and LAMTOR3/MAPKSP1 has been identified to interact with and recruit the four Rag GTPases to the surface of lysosomes (5).
Caculated MW:   18 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:250-1:500
IHC 1:200-1:500
IF 1-4 ug/mL
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information