AGP2746-11 [Polyclonal Antibody]
GLUD1 Goat Polyclonal Antibody
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Species:   Goat
Applications:   WB IHC ELISA
Immunogen Range:   A synthetic peptide corresponding to internal region of human GLUD1/GLUD2
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   2746
Swiss Prot:   P00367
Synonyms:   GDH, GDH1, GLUD, MGC132003
Purification:   Antigen affinity purification
Storage:   Store at -20°C in 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA).Avoid freeze/thaw cycles.
Background:   This gene encodes glutamate dehydrogenase protein; a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid induced insulin secretion and activating mutations in this gene are a common cause of congenital hyperinsulinism. This enzyme is allosterically activated by ADP and inhibited by GTP and ATP. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Multiple pseudogenes of this gene are present in humans
Caculated MW:   52 kDa
Observed MW:   Refer to Figures
Applications:   WB 0.1-0.3 ug/mL
IHC 3-5 ug/mL
Reacitivity:   Human, Mouse
For research use only. Not intended for diagnostic or therapeutic use!
Additional information