ARP5454-11 [Polyclonal Antibody]
POU3F2 Rabbit Polyclonal Antibody
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Species:   Goat
Applications:   WB ELISA
Immunogen Range:   A synthetic peptide corresponding to amino acids at N-terminus of human POU3F2
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   5454
Swiss Prot:   P20265
Synonyms:   BRN2, OCT7, OTF7, POUF3
Purification:   Antigen affinity purification
Storage:   Store at -20°C in 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA).Avoid freeze/thaw cycles.
Background:   POU3F2 belongs to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, that occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and Oct2 (POU2F2; MIM 164176) and the pituitary protein Pit1 (PIT1; MIM 173110). Class III POU genes are expressed predominantly in the central nervous system (CNS). It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression (Schreiber et al., 1993 [PubMed 8441633]; Atanasoski et al., 1995 [PubMed 7601453]).[supplied by OMIM
Caculated MW:   55 kDa
Observed MW:   Refer to Figures
Applications:   WB 0.1-0.3 ug/mL
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information