ARP3572-11
[Polyclonal Antibody]
IL6ST Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB IHC ELISA |
| Immunogen Range: | A synthetic peptide corresponding to residues surrounding S782 of human IL6ST |
| Clonality: | Polyclonal Antibody |
| Isotype: | / |
| GENE ID: | 3572 |
| Swiss Prot: | P40189 |
| Synonyms: | CD130, CDw130, GP130, GP130-RAPS, IL6R-beta |
| Purification: | Affinity purification |
| Storage: | Store at -20°C in PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).Avoid freeze/thaw cycles. |
| Background: | The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq |
| Caculated MW: | 130 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:1000 IHC 1:50-1:100 |
| Reacitivity: | Human, Mouse |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information