ARP7137-14 [Polyclonal Antibody]
TNNI3 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC ELISA
Immunogen Range:   A synthetic peptide corresponding to residues surrounding S43 of human TNNI3
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   7137
Swiss Prot:   P19429
Synonyms:   CMD2A, CMH7, MGC116817, RCM1, TNNC1, cTnI
Purification:   Affinity purification
Storage:   Store at -20°C in PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).Avoid freeze/thaw cycles.
Background:   Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq
Caculated MW:   28 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:1000
IHC 1:50-1:100
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information