ARP1387-12 [Polyclonal Antibody]
CREBBP Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC ELISA IF
Immunogen Range:   A synthetic peptide corresponding to N-terminus of human DOK7
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   1387
Swiss Prot:   Q92793
Synonyms:   C4orf25, Dok-7, FLJ33718, FLJ39137, FLJ90556
Purification:   Affinity purification
Storage:   Store at -20°C in PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol).Avoid freeze/thaw cycles.
Background:   The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Caculated MW:   300 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:1000
IHC 1:50-1:100
IF 1:500-1:1000
Reacitivity:   Human, Mouse
For research use only. Not intended for diagnostic or therapeutic use!
Additional information